Supplement Truth Engine — FDA/NIH Ingredient Analysis

FDA 2026 NIH ODS Impact Shield ✓
Impact Shield — Built by contact athletes, for contact athletes
The only supplement formula purpose-built for daily brain protection against subconcussive impact load — 13 evidence-backed ingredients across 32+ peer-reviewed studies, covering all five neuroprotection pillars (antioxidant, mitochondrial, anti-inflammatory, neurotransmitter, membrane). Paste any label below to see how it stacks up. See Impact Shield →
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Analysis Results
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FDA status · NIH evidence · dosage realism · red flags
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Impact Shield — Brain Support Formula for Contact Athletes
Built by an All-American football player and TSAC-F strength coach. 13 ingredients across 32+ peer-reviewed studies. Daily neuroprotection against cumulative subconcussive impact load. theimpactshield.com ↗
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Disease claims · drug language · FDA disclaimer
Head-to-Head vs Popular Brands
Full ingredient breakdown of each — click any card for the deep-dive comparison.
What would it cost to match Impact Shield yourself?
Pick the brain-protection pillars you want covered. See what a DIY stack of separate products runs vs. one Impact Shield.
Brain-Support & Athlete Recovery Stacks — How They Compare
Ranked by combined evidence for daily brain protection and impact recovery. Impact Shield is the only stack purpose-built as a full-spectrum formula for contact athletes — every other approach here covers only one or two of the mechanisms (antioxidant, mitochondrial, anti-inflammatory, neurotransmitter, membrane) that matter after subconcussive impact load.

FDA March 27, 2026 Meeting

"Exploring the Scope of Dietary Supplement Ingredients"

  • Reviewed "dietary substance for use by man" under DSHEA 1994
  • New manufacturing methodologies for existing ingredients
  • Proteins, enzymes, microbials as dietary ingredient categories
  • FDA launched Dietary Supplement Ingredient Directory
  • Public comments: Docket FDA-2026-N-2047 (closed Apr 27, 2026)
  • Key issue: NAC drug-exclusion — 2022 ruling vs. industry challenge ongoing

Evidence Grading Scale

GradeMeaning
AStrong — multiple large, well-designed RCTs
BModerate — some RCTs or consistent mechanistic + human data
CLimited — small/short trials, mixed results
DPoor — mostly animal/in vitro data
FNo credible evidence or proven ineffective

TBI/Brain evidence is graded separately from general fitness evidence where data differs.

Regulatory Status Codes

StatusMeaning
GRASGenerally Recognized As Safe
NDI AcceptedFDA accepted NDI (no objection)
NDI ObjectionFDA filed objection to NDI notification
Drug Excl. RiskFDA drug-exclusion clause may apply
NovelNo GRAS/NDI history; safety unestablished
BannedFDA enforcement — illegal in supplements
Drug IngredientApproved as a drug — illegal in supplements

Competition Compliance

WADA and NCAA banned-substance status shown per ingredient where relevant.

BadgeMeaning
PermittedNot on prohibited list
MonitorWatched/restricted in-competition
BannedProhibited substance

Always verify against current WADA/NCAA lists — rules change annually.